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Heroin also known as china white or α-Methylfentanyl (or alpha-Methylfentanyl) an opioid analgesic that is an analog of fentanyl. It is sometimes sold as “China White“.
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Buy White Heroin or α-Methylfentanyl was discovered by a team at Janssen Pharmaceutica in the 1960s.In 1976, it began to appear mixed with heroin, as an additive, and the mixture was sometimes also called “China White”.
It was first identified in the bodies of two drug overdose victims in Orange County, California, in December 1979, who appeared to have died from opiate overdose but tested negative for any known drugs of this type. Over the next year, there were 13 more deaths, and eventually the responsible agent was identified as α-methylfentanyl.
A bag of “China White” α-methylfentanyl.
α-Methylfentanyl was placed on the U.S. Following the appearance of α-methylfentanyl on the market, over ten new analogs of fentanyl have been reported, starting with para-fluorofentanyl, followed by α-methylacetylfentanyl, then by the highly potent 3-methylfentanyl, and subsequently by many others such as β-hydroxyfentanyl, ohmefentanyl, β-hydroxythiofentanyl and β-hydroxy-4-methylfentanyl.
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In 1991, a group of Russian chemistry students discovered a simplified synthesis route which used phosgene instead of phenethylamine. Soon, abuse of the drug became widespread, causing a tenth of overdoses in the Moscow region. α-Methylfentanyl became notorious for low safety, and production declined.
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Heroin (Diacetylmorphine) is derived from the morphine alkaloid found in opium and is roughly 2-3 times more potent. A highly addictive drug, heroin exhibits euphoric (“rush”), Anxiolytic and analgesic central nervous system properties.
Methods of Heroin Use
Smoking and sniffing heroin do not produce a “rush” as quickly or as intensely as intravenous injection. Oral ingestion does not usually lead to a “rush”. But use of heroin in suppository form may have intense euphoric effects. buy heroin online.
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Heroin paraphernalia or α-Methylfentanyl has similar effects to fentanyl. It is less potent by weight due to reduced binding affinity to its target site, yet longer acting as the α-methyl group interferes with binding to metabolic enzymes which break the drug down.
The independent discovery of the effect of the α-methyl group on fentanyl also marked the first time clandestine recreational-drug research had an effect on practical scientific research.
Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression (namely with overdoses or improper drug-combinations, such as with benzodiazepines) which can be life-threatening.
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Common side effects include respiratory depression (decreased breathing), dry mouth, drowsiness, impaired mental function, constipation, and addiction. Use by injection can also result in abscesses, infected heart valves, blood-borne infections, and pneumonia.
After a history of long-term use, opioid withdrawal symptoms can begin within hours of the last use. When given by injection into a vein, heroin has two to three times the effect of a similar dose of morphine. It typically appears in the form of a white or brown powder.
Treatment of heroin addiction often includes behavioral therapy and medications. Medications can include buprenorphine, methadone, or naltrexone. A heroin overdose may be treated with naloxone.
An estimated 17 million people as of 2015 use opiates, of which heroin is the most common, and opioid use resulted in 122,000 deaths. The total number of heroin users worldwide as of 2015 is believed to have increased in Africa, the Americas, and Asia since 2000.
In the United States, approximately 1.6 percent of people have used heroin at some point, with 950,000 using it in the last year. When people die from overdosing on a drug, the drug is usually an opioid and often heroin
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is a form of heroin that is sticky like tar or hard like coal. Its dark color is the result of crude processing methods that leave behind impurities. Despite its name, black tar heroin can also be dark orange or dark brown in appearance.
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Intravenous use of heroin (and any other substance) with needles and syringes or other related equipment may lead to:
Contracting blood-borne pathogens such as HIV and hepatitis via the sharing of needles
Contracting bacterial or fungal endocarditis and possibly venous sclerosis
Poisoning from contaminants added to “cut” or dilute heroin
Decreased kidney function (nephropathy), although it is not currently known if this is because of adulterants or infectious diseases
The withdrawal syndrome from heroin may begin within as little as two hours of discontinuation of the drug; however, this time frame can fluctuate with the degree of tolerance as well as the amount of the last consumed dose, and more typically begins within 6–24 hours after cessation.
Symptoms may include sweating, malaise, anxiety, depression, akathisia, priapism, extra sensitivity of the genitals in females, general feeling of heaviness, excessive yawning or sneezing, rhinorrhea, insomnia, cold sweats, chills, severe muscle and bone aches, nausea, vomiting, diarrhea, cramps, watery eyes,fever, cramp-like pains, and involuntary spasms in the limbs (thought to be an origin of the term “kicking the habit”
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